1.Small molecule inhibits KCNQ channels with a non-blocking mechanism

Li, JN, Yang, ZN, Zh     More...

Li, JN, Yang, ZN, Zhang, SY, Ye, YL, He, JN, Zhang, Y, Han, HY, Kong, W, Liu, JR, Min, Y, Shen, JW, Mei, LH, Chen, ZS, Hou, PP, Guo, JT, Zhang, QS, Yang, HY     Less

NATURE CHEMICAL BIOLOGY[1552-4450], Published 2025,

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WOS核心合集引用: 0  2024影響因子:  13.7 

2.A small-molecule activation mechanism that directly opens the KCNQ2 channel

Zhang, SY, Ma, DM, W     More...

Zhang, SY, Ma, DM, Wang, K, Li, Y, Yang, ZN, Li, XX, Li, JN, He, JN, Mei, LH, Ye, YL, Chen, ZS, Shen, JW, Hou, PP, Guo, JT, Zhang, QS, Yang, HY     Less

NATURE CHEMICAL BIOLOGY[1552-4450], Published 2024,

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WOS核心合集引用: 13  2024影響因子:  13.7  发表年影響因子:  13.7 

3.Targeting the IKs Channel PKA Phosphorylation Axis to Restore Its Function in High-Risk LQT1 Variants

Zhong, Ling, Yan, Zh     More...

Zhong, Ling, Yan, Zhenzhen, Jiang, Dexiang, Weng, Kuo Chan, Ouyang, Yue, Zhang, Hangyu, Lin, Xiaoqing, Xiao, Chenxin, Yang, Huaiyu, Yao, Jing, Kang, Xinjiang, Wang, Changhe, Huang, Chen, Shen, Bing, Chung, Sookja Kim, Jiang, Zhi Hong, Zhu, Wandi, Neher, Erwin, Silva, Jonathan R., Hou, Panpan     Less

Circulation Research[0009-7330], Published 2024, Volume 135, Issue 7, Pages 722-738

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WOS核心合集引用: 1  2024影響因子:  16.2  发表年影響因子:  16.2 

4.The fully activated open state of KCNQ1 controls the cardiac "fight-or-flight" response

Hou, PP, Zhao, L, Zh     More...

Hou, PP, Zhao, L, Zhong, L, Shi, JY, Wang, HZ, Gao, JY, Liu, HL, Zuckerman, J, Cohen, IS, Cui, JM     Less

PNAS NEXUS[2752-6542], Published 2024, Volume 3, Issue 10,

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WOS核心合集引用: 0  2024影響因子:  3.8  发表年影響因子:  3.8 

5.Chinese herbal medicine for the treatment of cardiovascular diseases - Targeting cardiac ion channels

Yan, ZZ, Zhong, L, Z     More...

Yan, ZZ, Zhong, L, Zhu, WD, Chung, SK, Hou, PP     Less

PHARMACOLOGICAL RESEARCH[1043-6618], Published 2023, Volume 192,

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WOS核心合集引用: 12  2024影響因子:  10.5  发表年影響因子:  9.1 

6.Ligand activation mechanisms of human KCNQ2 channel

Ma, Demin, Zheng, Yu     More...

Ma, Demin, Zheng, Yueming, Li, Xiaoxiao, Zhou, Xiaoyu, Yang, Zhenni, Zhang, Yan, Wang, Long, Zhang, Wenbo, Fang, Jiajia, Zhao, Guohua, Hou, Panpan, Nan, Fajun, Yang, Wei, Su, Nannan, Gao, Zhaobing, Guo, Jiangtao     Less

Nature Communications[2041-1723], Published 2023, Volume 14, Issue 1,

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WOS核心合集引用: 18  2024影響因子:  15.7  发表年影響因子:  14.7 

7.Structural mechanisms for the activation of human cardiac KCNQ1 channel by electro-mechanical coupling enhancers

Ma, DM, Zhong, L, Ya     More...

Ma, DM, Zhong, L, Yan, ZZ, Yao, J, Zhang, Y, Ye, F, Huang, Y, Lai, DW, Yang, W, Hou, PP, Guo, JT     Less

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[0027-8424], Published 2022, Volume 119, Issue 45,

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WOS核心合集引用: 19  2024影響因子:  9.1  发表年影響因子:  11.1 

8.Editorial: Ion Channels: Therapeutic Targets for Neurological Disease

Hou, PP, Du, XN, An,     More...

Hou, PP, Du, XN, An, HL     Less

FRONTIERS IN MOLECULAR NEUROSCIENCE[1662-5099], Published 2021, Volume 14,

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WOS核心合集引用: 1  2024影響因子:  3.8  发表年影響因子:  6.261 

9.A PIP2 substitute mediates voltage sensor-pore coupling in KCNQ activation

Liu, YF, Xu, XJ, Gao     More...

Liu, YF, Xu, XJ, Gao, JY, Naffaa, MM, Liang, HW, Shi, JY, Wang, HZ, Yang, ND, Hou, PP, Zhao, WS, White, KM, Kong, WJ, Dou, A, Cui, A, Zhang, GH, Cohen, IS, Zou, XQ, Cui, JM     Less

COMMUNICATIONS BIOLOGY[2399-3642], Published 2020, Volume 3, Issue 1,

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WOS核心合集引用: 27  2024影響因子:  5.1  发表年影響因子:  6.268 

10.Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state

Taylor, KC, Kang, PW     More...

Taylor, KC, Kang, PW, Hou, PP, Yang, ND, Kuenze, G, Smith, JA, Shi, JY, Huang, H, White, KM, Peng, DG, George, AL, Meiler, J, McFeeters, RL, Cui, JM, Sanders, CR     Less

ELIFE[2050-084X], Published 2020, Volume 9,

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WOS核心合集引用: 37  2024影響因子:  N/A  发表年影響因子:  8.146 

11.Two-stage "Hand-and-Elbow" Gating Mechanism of a K-V Channel

Hou, PP, Kang, PW, K     More...

Hou, PP, Kang, PW, Kongmeneck, AD, Yang, ND, Liu, YF, Shi, JY, Xu, XJ, White, KM, Zaydman, MA, Kasimova, MA, Seebohm, G, Zhong, L, Zou, XQ, Tarek, M, Cui, JM     Less

BIOPHYSICAL JOURNAL[0006-3495], Published 2020, Volume 118, Issue 3, Pages 113A-113A

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WOS核心合集引用: 0  2024影響因子:  3.1  发表年影響因子:  4.033 

12.Gating Mechanisms of Cardiac and Neuronal KCNQ Potassium Channels

Yang, ND, Dou, A, Ka     More...

Yang, ND, Dou, A, Kang, PW, Hou, PP, White, KM, Shi, JY, Cui, JM     Less

BIOPHYSICAL JOURNAL[0006-3495], Published 2020, Volume 118, Issue 3, Pages 264A-264A

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WOS核心合集引用: 0  2024影響因子:  3.1  发表年影響因子:  4.033 

13.Structure and Physiological Function of the KCNQ1 Channel Voltage Sensor Intermediate State

Sanders, CR, Taylor,     More...

Sanders, CR, Taylor, KC, Kang, PW, Hou, PP, Yang, ND, Kuenze, G, George, AL, Meiler, J, McFeeters, RL, Cui, JM     Less

BIOPHYSICAL JOURNAL[0006-3495], Published 2020, Volume 118, Issue 3, Pages 333A-333A

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WOS核心合集引用: 0  2024影響因子:  3.1  发表年影響因子:  4.033 

14.Two-stage electro-mechanical coupling of a K-V channel in voltage-dependent activation

Hou, P, Kang, PW, Ko     More...

Hou, P, Kang, PW, Kongmeneck, AD, Yang, ND, Liu, YF, Shi, JY, Xu, XJ, White, KM, Zaydman, MA, Kasimova, MA, Seebohm, G, Zhong, L, Zou, XQ, Tarek, M, Cui, JM     Less

NATURE COMMUNICATIONS[2041-1723], Published 2020, Volume 11, Issue 1,

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WOS核心合集引用: 42  2024影響因子:  15.7  发表年影響因子:  14.919 

15.ML277 specifically enhances the fully activated open state of KCNQ1 by modulating VSD-pore coupling

Hou, PP, Shi, JY, Wh     More...

Hou, PP, Shi, JY, White, KM, Gao, Y, Cui, JM     Less

ELIFE[2050-084X], Published 2019, Volume 8,

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WOS核心合集引用: 26  2024影響因子:  N/A  发表年影響因子:  7.080 

16.A Non-Canonical VSD-Pore Coupling in KCNQ Channels

Hou, PP, Shi, JY, Cu     More...

Hou, PP, Shi, JY, Cui, JM     Less

BIOPHYSICAL JOURNAL[0006-3495], Published 2019, Volume 116, Issue 3, Pages 303A-303A

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WOS核心合集引用: 0  2024影響因子:  3.1  发表年影響因子:  3.854 

17.CP1 Is a Potent I-Ks Channel Activator Which Acts by Substituting Phosphatidylinositol 4,5 Bisphosphate

Liu, YF, Xu, XJ, Naf     More...

Liu, YF, Xu, XJ, Naffaa, MM, Liang, HW, Zhang, GH, Hou, PP, Wang, HZ, Gao, JY, Shi, JY, Cohen, I, Zou, XQ, Cui, JM     Less

BIOPHYSICAL JOURNAL[0006-3495], Published 2019, Volume 116, Issue 3, Pages 542A-543A

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WOS核心合集引用: 0  2024影響因子:  3.1  发表年影響因子:  3.854 

18.Structure of the Intermediate State of the Human KCNQ1 Channel Voltage-Sensor Domain

Taylor, KC, Kang, PW     More...

Taylor, KC, Kang, PW, Hou, PP, Yang, ND, Kuenze, G, Shi, JY, Smith, JA, White, KM, Huang, H, Peng, DG, George, AL, Meiler, J, McFeeters, RL, Cui, JM, Sanders, CR     Less

BIOPHYSICAL JOURNAL[0006-3495], Published 2019, Volume 116, Issue 3, Pages 542A-542A

收錄情况： WOS

WOS核心合集引用: 0  2024影響因子:  3.1  发表年影響因子:  3.854 

19.Predicting Patient Response to the Antiarrhythmic Mexiletine Based on Genetic Variation Personalized Medicine for Long QT Syndrome

Zhu, WD, Mazzanti, A     More...

Zhu, WD, Mazzanti, A, Voelker, TL, Hou, PP, Moreno, JD, Angsutararux, P, Naegle, KM, Priori, SG, Silva, JR     Less

CIRCULATION RESEARCH[0009-7330], Published 2019, Volume 124, Issue 4, Pages 539-552

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WOS核心合集引用: 42  2024影響因子:  16.2  发表年影響因子:  14.467 

20.A Non-canonical VSD-Pore Coupling is Responsible for the AO State of KCNQ1 Channels

Hou, PP     More...

Hou, PP     Less

BIOPHYSICAL JOURNAL[0006-3495], Published 2018, Volume 114, Issue 3, Pages 122A-122A

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WOS核心合集引用: 0  2024影響因子:  3.1  发表年影響因子:  3.665