2023-2026 [澳門科學技術發展基金項目/ FDCT Projects] UNC5C netrin受體在腸神經系統發育和引致先天性巨結腸的分子機制 = Molecular mechanisms of UNC5C netrin receptor in the development of enteric nervous system and pathogenesis of Hirschsprung disease  (Principal Investigator)

2022-2026 [Hong Kong Science and Technology Parks] GLOAS Limited. Incu-Bio Programme  (Principal Investigator)

2022-2023 [澳門科技大學研究基金(FRG)項目)/ MUST Faculty Research Grant Projects] ABCA1基因表達改變對小鼠膽道上皮類器官發育及功能的影響 = The study of ABCA1 dysregulation on the developmental and functional effects of biliary organoid in mic  (Principal Investigator)

2021-2022 [Research Grant Council Theme-based Research Scheme] Translating Disease-Mechanism Discoveries to Improve Treatment of Biliary Atresia, an Intractable Newborn Liver Disease  (Principal Investigator)

2020-2021 [RGC Collaborative Research Fund/CRF] Comparison of paediatric and adult responses to coronavirus infection – a molecular, cellular and tissue study  (Principal Investigator)

2020-2021 [RGC General Research Fund] Modelling disease mechanisms and risks of congenital bile-duct dilatation using whole exome sequencing and SNP array data  (Principal Investigator)

2019-2021 [Seed Fund for Basic Research] Whole exome sequencing of 8 trios devoid of mutation in the main genes known to underly Hirschsprung disease  (Principal Investigator)

2018-2020 [Health and Medical Research Fund/HMRF] Functional genetic study to unravel the genetic background of choledochal cyst  (Principal Investigator)

2018-2019 [RGC General Research Fund] The biliary atresia genome: a pilot study to model disease from whole genome sequencing data  (Principal Investigator)

2016-2018 [Health and Medical Research Fund/HMRF] Decoding biliary atresia at the transcriptome and tissue architecture level  (Principal Investigator)

2016-2018 [Seed Funding Programme for Basic Research] CDD55 and biliary atresia  (Principal Investigator)

2015-2017 [RGC General Research Fund] Using genome-editing system to establish human stem cell-based disease model for studying Hirschsprungs (HSCR) associated genetic lesions  (Principal Investigator)

2015-2019 [Theme-based Research Scheme] Genetics and functional genomics of neural crest stem cells and associated disease: Hirschsprung disease  (Principal Investigator)

2014-2016 [Seed Funding Programme for Basic Research] Generation of isogenic human embryonic stem cells for modeling Hirschsprung's disease  (Principal Investigator)

2013-2014 [RGC General Research Fund] Uncovering the genetic lesions underlying persistent cloaca by whole genome sequencing  (Principal Investigator)

2012-2013 [RGC General Research Fund] Study on genomic structural variations in Hirschsprung disease  (Principal Investigator)

2012-2014 [S.K. Yee Medical Foundation] Advancing laparoscopic skills in China – an extension of the current laparoscopic workshop scheme  (Principal Investigator)

2012-2014 [Seed Funding Programme for Basic Research] Study of de novo copy number variations (CNV) in Hirschsprung disease  (Principal Investigator)

2011-2012 [The Graduate Research Fund/GRF] Study on genomic structural variations in Hirschsprung's disease GRF Incentive Award (Principal Investigator)

2011-2013 [Seed Funding Programme for Basic Research] Validation of NRG3 copy number variations in the genome of Hirschsprung's patients  (Principal Investigator)

2010-2013 [RGC General Research Fund] Deep re-sequencing of Hirschsprung's disease candidate genes  (Principal Investigator)

2010-2012 [S.K. Yee Medical Foundation] Establishing S.K. Yee Medical Foundation clinical fellowships  (Principal Investigator)

2010-2012 [Seed Funding Programme for Basic Research] NRG1 intron 1 SNPs in Hirschsprung's disease  (Principal Investigator)

2009-2011 [S.K. Yee Medical Foundation] Improving the surgical care of sick children in Hong Kong by providing cutting edge minimally invasive and robotic surgery  (Principal Investigator)

2008-2009 [France/Hong Kong Joint Research Scheme] Dissecting Hirschsprung's disease: international Hirschsprung's disease consortium  (Principal Investigator)

2008-2011 [RGC General Research Fund] Genome-wide association study for the identification of genes underlying anorectal malformation  (Principal Investigator)

2008-2010 [S.K. Yee Medical Foundation] Offering surgical care to poor children with major congenital anomalies in rural China  (Principal Investigator)

2008-2010 [S.K. Yee Medical Foundation] Establishing a quaternary paediatric gastrointestinal centre for Hong Kong  (Principal Investigator)

2008-2010 [URC Seed Funding for Basic Research] Sequencing of the HOXD13 gene in patients with anorectal malformations  (Principal Investigator)

2007-2008 [RGC General Research Fund] Study of the genetic basis of biliary atresia  (Principal Investigator)

2007-2010 [RGC General Research Fund] Genetic dissection of Hirschsprung's disease  (Principal Investigator)

2007-2009 [S.K. Yee Medical Foundation] Offering laparoscopic surgical workshops in China  (Principal Investigator)

2007-2009 [URC Seed Funding for Basic Research] Whole genome family based association study to search for RET-dependent modifiers in Hirschsprung's disease  (Principal Investigator)

2005-2010 [S.K. Yee Medical Foundation] Further expansion of the “Train-the-Trainers” programme for paediatric surgery in China  (Principal Investigator)

2004-2005 [CRCG] Evaluation of HOXB5 as a new Hirschsprung's disease susceptibility locus  (Principal Investigator)

2004-2005 [University's Incentive Award] T cell memory and chronic rejection  (Principal Investigator)

2003-2004 [CRCG] The study of co-stimulatory function of sonic hedgehog in CD4+ lymphocytes  (Principal Investigator)

2003-2007 [S.K. Yee Medical Foundation Grant] Improving the survival and quality of life of children with cancers in China  (Principal Investigator)

2003-2004 [University's Incentive Award] The role of T regulatory cell in the long-term survival of orthotropic small bowel allograft  (Principal Investigator)

2002-2005 [RGC General Research Fund] Sonic hedgehog signalling in chronic allograft rejection  (Principal Investigator)

2002-2003 [URC Seed Funding] The study of T regulatory cell in the indefinite survival of orthotropic small bowel allograft  (Principal Investigator)

2001-2004 [RGC General Research Fund] OX40/OX40L-costimulatory pathway in transplantation rejection and tolerance induction  (Principal Investigator)

2001-2002 [URC Seed Funding] Investigation of the role of Sox10 gene in enteric nervous system development by explant and organ culture systems  (Principal Investigator)

2000-2001 [France/Hong Kong Joint Research Scheme] Analysis of single nucleotide polymorphism (SNPs) of the RET protooncogene in RET associated diseases  (Principal Investigator)

2000-2002 [RGC General Research Fund] Multiple molecular approaches for elucidating the multigenic nature of Hirschsprung's disease in Chinese patients  (Principal Investigator)

2000-2003 [S.K. Yee Medical Foundation] Expanding the "Train-the-Trainers" programme for paediatric surgery in China  (Principal Investigator)

2000-2001 [URC Seed Funding] High throughput analysis of expression profile of genes implicated in enteric neural development and in Hirschsprung's disease in human  (Principal Investigator)

1999-2000 [CRCG (seed-funding)] Molecular mechanisms of intestinal ischaemia-reperfusion injury  (Principal Investigator)

1999-2001 [Faculty of Medicine(Research Officer appointment in support of Centres of Excellence under the Faculty and Inter-departmental Collaborative Projects)] Molecular mechanisms of intestinal transplant failures: ischaemia-reperfusion injury and immunological rejection  (Principal Investigator)

1999-2000 [France/Hong Kong Joint Research Scheme] Analysis of somatic mutations of the ret protooncogene in ret associated diseases  (Principal Investigator)

1999-1999 [Fujisawa] New methods of immunosuppression in allogenic small bowel transplantation  (Principal Investigator)

1999-2002 [Postdoctoral Fellowship Schemes, University of Hong Kong] Transgenesis animals as bioreactors  (Principal Investigator)

1998-1999 [CRCG] Molecular studies of transcription factors implicated in enteric neural development and in Hirschsprung's disease  (Principal Investigator)

1998-2000 [Research Associate Professorship Scheme, University of Hong Kong] Molecular study of neural crest disorders  (Principal Investigator)

1998-2000 [RGC General Research Fund] Immune mechanisms and new immunosuppressive approaches in small bowel transplantation  (Principal Investigator)

1998-2001 [S.K. Yee Medical Foundation] Establishing a “Train-the-Trainers' programme for paediatric surgery in China  (Principal Investigator)

1998-2000 [UK/Hong Kong Joint Research Scheme, British Council] The role of neurotrophic factors in Hirschsprung's disease and idiopathic slow transit constipation - a common link?  (Principal Investigator)

1997-1998 [Chinese Medicine Research, HKU] Immunosuppressive properties of Tripterygium wolfordii in small bowel transplantation  (Principal Investigator)

1997-1998 [Research Student Support Fund] Intestinal failure and experimental small bowel transplantation  (Principal Investigator)

1997-1998 [Rotary Club of Kowloon East] Improvement of the care of children with vomiting  (Principal Investigator)

1997-1999 [Vice-Chancellor's Development Fund] Transgenesis animals as bioreactors: production of a new immunosuppressive protein CTLA4Ig by transgenesis  (Principal Investigator)

1996-1999 [CRCG] Genetic analysis of Hirschsprung's disease (intestinal aganglionosis): clinical pathological-epidemiological correlation  (Principal Investigator)

1996-1996 [Fujisawa] New methods of immunosuppression in allogenic small bowel transplantation  (Principal Investigator)

1995-1996 [Action Research] Novel immunosuppression in allogenic small bowel transplantation  (Principal Investigator)

1995- [Mason Medical Research Foundation] A novel approach to immunosuppression in small bowel transplantation using a HLA class 1 - derived peptide  (Principal Investigator)

1995- [Peel Medical Research Trust] Characterisation and identification of genes for Hirschsprung's disease  (Principal Investigator)

1995- [Royal College of Surgeons of Edinburgh] The effect of FK506 recipient pretreatment on intragraft cytokine gene expression following small bowel transplantation in rats  (Principal Investigator)

1995- [Sir Edward Penley Abraham Research Fund] New approaches of immunosuppression in small bowel transplantation  (Principal Investigator)

1994- [Medical Research Fund, University of Oxford] Molecular mechanisms regulating neural crest cell migration in gut during early development  (Principal Investigator)

1994- [Royal College of Surgeons of England Research Fellowship] Immune mechanisms of rejection in combined small bowel - liver transplantation  (Principal Investigator)

1993-1996 [The Children's Research Fund] Immunological mechanisms of rejection in small bowel transplantation and their modulation with new methods of immunosuppression  (Principal Investigator)

1992-1993 [Medical Research Fund, University of Oxford] Immunological mechanisms of rejection of small bowel transplantation  (Principal Investigator)

1992- [Peel Medical Trust] Immunological mechanisms of rejection of small bowel transplantation  (Principal Investigator)

1991-1996 [John Radcliffe Hospital, Oxford] Immunological mechanisms of rejection of small bowel transplantation  (Principal Investigator)

1991- [Medical Insurance Agency Charity] Molecular mechanisms regulating neural crest cell migration in gut during early development  (Principal Investigator)

1991-1996 [Oxford Regional Health Authority] Molecular mechanisms regulating neural crest cell migration in gut during early development  (Principal Investigator)

1990-1991 [Alder Hey children's Hospital Trust Funds] An immunohistochemical study of Hirschsprung's Disease and related disorders  (Principal Investigator)

1990-1991 [The Children's Research Fund] An immunohistochemical study of Hirschsprung's Disease and related disorders  (Principal Investigator)

1990- [Wellcome Trust] Molecular biological investigations into the relationship between cytomegalovirus and Hirschsprung's Disease  (Principal Investigator)

1989- [Wellcome Trust] Neuron cell adhesion molecules in aganglionic colon in mouse and man  (Principal Investigator)

1988- [University of Liverpool Research Grant] Anorectal manometry for bowel motility problems in children  (Principal Investigator)

1986-1989 [The Children's Research Fund] Development and abnormalities of enteric nervous system  (Principal Investigator)

1986-1987 [Wing Lung Bank Medical Research Fund] Serum gastrin and pepsinogen 1 levels in surgical subjects  (Principal Investigator)

1985-1986 [University Research Grant (Hong Kong)] Serum gastrin and pepsinogen 1 levels in surgical subjects  (Principal Investigator)

- [Health and Medical Research Fund/HMRF] Whole exome sequencing to uncover genetics variants underlying congenital cystic adenomatoid malformations  (Principal Investigator)

- [Health and Medical Research Fund Commissioned PaediatricResearch] Molecular diagnosis of rare genetic diseases: whole genome sequencing and transcriptomics of biliary atresia, Hirschsprung disease and congenital pulmonary airway malformations  (Principal Investigator)

- [Health and Medical Research Fund Commissioned PaediatricResearch] To elucidate the role of ‘niche' factors in the pathogenesis of Biliary Atresia using an advanced organoid system  (Principal Investigator)

- [Innovation and Technology Fund University-Industry Collaboration Programme] Advancing Diagnosis and Treatment of Two Liver Diseases, Alagille Syndrome and Biliary Atresia, by Organoid and Single Cell Transcriptome Analysis  (Principal Investigator)

- [Innovation and Technology Fund University-Industry Collaboration Programme] Establishment of new treatment strategy for neurological diseases using patient specific induced pluripotent stem cells and high-resolution single cell sequencing  (Principal Investigator)

2003- [The Croucher Foundation] Croucher Advanced Study Institute: Advances and Challenges of Stem Cell Research  

2003-2004 [The University of Hong Kong Foundation for Education Development and Research] Biotech Company in the Faculty of Medicine, HKU  

2001- [The Croucher Foundation] Croucher Advanced Study Institute: Fundamentals of Human Genetics and Genomic Biology  

2000- [Seeding-funding, Faculty of Medicine] Center of Human Development and Birth Defects  

2000- [The Croucher Foundation] Croucher Advanced Study Institute: Genetics, Health and Disease in the Post Genome Project Era  

2020-2021 [RGC General Research Fund] A novel bioinformatics framework for curating and analyzing structural variations from whole genome sequencing data  (Co-Investigator)

2019-2021 [Health and Medical Research Fund/HMRF] A sensitized genetic screen to identify and functionally characterize genetic modifiers for Hirschsprung disease  (Co-Investigator)

2019-2021 [RGC General Research Fund] Functional genomics to investigate cholangiocyte cilia dysfunctions in biliary atresia  (Co-Investigator)

2017-2019 [Health and Medical Research Fund/HMRF] Identification and functional characterization of Hirshsprung disease susceptibility genes on chromosome 21  (Co-Investigator)

2016-2018 [Innovation and Technology Support Programme (Tier 2)] Establishing a molecular encyclopedia for stem cell and regenerative medicine: Heart  (Co-Investigator)

2015-2017 [Health and Medical Research Fund/HMRF] The International Hirschsprung Disease Consortium: follow-up on whole-exome sequencing data  (Co-Investigator)

2015-2017 [Seed Funding Programme for Basic Research] Anorectal malformations: transethnic follow-up on DDK4  (Co-Investigator)

2014-2017 [RGC General Research Fund] Causative genes for perinatal biliary atresia: a follow-up of whole-exome sequencing  (Co-Investigator)

2014-2016 [Seed Funding Programme for Basic Research] Villin 1 (VIL1) mutations in biliary atresia patients: a coincidence?  (Co-Investigator)

2014-2016 [Seed Funding Programme for Basic Research] Do de novo chromosomal abnormalities lead to sporadic biliary atresia?  (Co-Investigator)

2014-2015 [Small Project Funding] Copy number variation in syndromic Hirschsprung disease patients  (Co-Investigator)

2013-2014 [Health and Medical Research Fund/HMRF] Uncovering the genetic lesions underlying the most severe form of Hirschsprung (HSCR) disease by whole genome sequencing (WGS): a pilot study in 8 family trios  (Co-Investigator)

2013-2014 [Health and Medical Research Fund/HMRF] Potential use of patient specific induced-pluriopotent stem cell (iPSC) to define genetic lesions contributing to the disease phenotypes of syndromic Hirschsprung (HSCR)  (Co-Investigator)

2013-2014 [Health and Medical Research Fund/HMRF] Functional genetics study to unravel the genetic background of a complex neurodevelopmental disorder namely Hirschsprung disease  (Co-Investigator)

2013-2014 [RGC General Research Fund] Congenital dilatation of the bile ducts (CCD): a genetic study  (Co-Investigator)

2012-2013 [RGC General Research Fund] Whole-exome sequencing to uncover causative genes for perinatal biliary atresia  (Co-Investigator)

2011-2012 [RGC General Research Fund] Whole-exome sequencing to identify genes underlying Caudal Regression Syndrome  (Co-Investigator)

2011-2012 [RGC General Research Fund] Transcriptional regulation of RET in Hirschsprung's disease  (Co-Investigator)

2011-2013 [Seed Funding Programme for Basic Research] Investigation of structural variations in Caudal Regression Syndrome Patients  (Co-Investigator)

2011-2013 [Seed Funding Programme for Basic Research] Meta-analysis of Chinese and European genome-wide association studies of Hirschsprung's disease and confirmation of novel loci  (Co-Investigator)

2010-2012 [Innovation and Technology Support Programme] Next generation high-throughput and targeted DNA sequencing platforms for systematic discovery of novel diagnostic markers of common disease  (Co-Investigator)

2010-2011 [RGC General Research Fund] Prokineticin signalling in neuroblastoma  (Co-Investigator)

2010-2011 [RGC General Research Fund] Premature gliogenesis of enteric neural crest cells induced by aberrant Sonic hedgehog-Notch signalling: a cause of Hirschsprung diseases?  (Co-Investigator)

2010-2012 [S.K. Yee Medical Foundation] Development of minimally invasive surgery service for children in centres in rural China  (Co-Investigator)

2010-2012 [Seed Funding Programme for Basic Research] Exon sequencing of Semaphorin, a novel Hirschsprung's disease susceptibility locus  (Co-Investigator)

2009-2010 [RGC General Research Fund] Fine mapping of Hirschsprung's disease loci on the 3p21 and 9q31 candidate regions  (Co-Investigator)

2009-2011 [RGC General Research Fund] Thyroid transcription factor-1 (TTF-1), a potential susceptibility gene for familial papillary thyroid carcinoma  (Co-Investigator)

2009-2011 [RGC General Research Fund] Identification of functional variants in Neuregulin-1 (NRG1), a newly discovered Hirschsprung disease gene  (Co-Investigator)

2009-2011 [Seed Project Funding] Inkjet printing of tissue-engineered skin construct for vascular regeneration in wound healing  (Co-Investigator)

2008-2011 [RGC General Research Fund] Genome-wide association study of schizophrenia  (Co-Investigator)

2008-2010 [RGC General Research Fund] Functional evaluation of RET coding and non-coding sequence mutations in Hirschsprung's disease  (Co-Investigator)

2008-2011 [RGC General Research Fund] HOXB5 and RET promoter: regulation of RET transcription in Hirschsprung's disease  (Co-Investigator)

2008-2010 [RGC General Research Fund] The role of adiponectin in cardiac allograft survival and immune regulation  (Co-Investigator)

2007-2009 [RGC General Research Fund] Investigation of cell autonomous function of Hedgehog signaling on vagal neural crest cells by conditional knockout of Smoothened in mice  (Co-Investigator)

2007-2010 [RGC General Research Fund] Molecular characterization of the transcriptional regulatory elements involved in the synergistic induction of heme oxygenase-1 expression by traditional Chinese medicines  (Co-Investigator)

2007-2008 [URC Seed Funding] Functional analysis of RET coding region mutations  (Co-Investigator)

2006-2008 [RGC General Research Fund] Study of the molecular basis of anorectal malformations  (Co-Investigator)

2005-2008 [RGC General Research Fund] Functional analysis of Hoxb5 in enteric neurons in mice  (Co-Investigator)

2005-2008 [RGC General Research Fund] Investigating the moleculars basis of Sox10 functions in enteric nervous system development using a series of mutant mouse models  (Co-Investigator)

2005-2006 [URC Seed Funding] Study of the molecular basis of anorectal malformations  (Co-Investigator)

2004-2006 [RGC General Research Fund] Conditional knockout of Patched gene in enteric neural crest cells: functional study of the role of Hedgehog signaling in enteric nervous system development  (Co-Investigator)

2004-2007 [RGC General Research Fund] RET regulatory polymorphisms and susceptibility to Hirschsprung's disease  (Co-Investigator)

2003- [Innovation and Technology Fund] A haplotype map (HapMap) of the human genome – Hong Kong contribution  (Co-Investigator)

2003-2005 [RGC General Research Fund] Regulation of gene transcription by NF-kB and stats downstream of the ret receptor tyrosine kinase in Hirschsprung disease and thyroid cancer  (Co-Investigator)

2003-2005 [RGC General Research Fund] Epigenetic and genetic deregulation in pediatric solid tumors  (Co-Investigator)

2003- [University Grant Committee] A haplotype map (HapMap) of the human genome – Hong Kong contribution  (Co-Investigator)

2002-2004 [RGC General Research Fund] Engrailed-Hoxb5 chimaeric transcription repressor: a novel approach to investigate Hoxb5 function in enteric neurons and gut development in transgenic mice  (Co-Investigator)

2001- [URC Seed Funding] The effect of tryptophan metabolism on the regulation of function and migration of dendritic cells  (Co-Investigator)

2000- [Queen Mary Hospital Charity Ltd - Training and Research Assistant Scheme] Can nitric oxide donors protect premature babies from necrotising enterocolitis  (Co-Investigator)

2000-2001 [RGC Earmarked Grants] Defining the role of RET receptor tyrosine kinase in enteric neurogenesis  (Co-Investigator)

2000- [URC Seed Funding] Role of GFRs in the development of enteric nervous system and in the aetiology of Hirschsprung's disease  (Co-Investigator)

2000- [URC Seed Funding] Novel approach in induction of donor specific tolerance in small bowel transplantation model in rat: a pre-clinical study  (Co-Investigator)

2000- [URC Seed Funding] Study the expression of 3' splicing veriants of RET protooncogene in mouse embryogenesis  (Co-Investigator)

2000- [URC Seed Funding] Pathogenetic role of macrophage migration inhibitory factor in necrotizing enterocolitis  (Co-Investigator)

1999-2000 [CRCG] Inner ear abnormalities in children with Hirschsprung's disease  (Co-Investigator)

1999-1999 [France/Hong Kong Joint Research Scheme] Studying the role of Sox 10 and Krox-20 genes in the migration and differentiation of vagel neural crest cells using the Dominant megacolon mutant mice  (Co-Investigator)

1999- [RGC Earmarked Grants] Transgenic mouse models for studying the role of mouse SOX10 gene in enteric nervous system development  (Co-Investigator)

1998-1999 [CRCG] Hirschsprung's disease may not be a localised neuropathy: an intestinal transit and autonomic and sensory nerve function study  (Co-Investigator)

1997-1998 [Chinese Medicine Research, HKU] Acupressure for the prevention of nausea and vomiting complicating chemotherapy in children: an electrogastrographic study  (Co-Investigator)

1997-1998 [CRCG] The effect of adriamycin on apoptosis in recanalization of duodenum in fetal rats  (Co-Investigator)

1997-1998 [CRCG] Ileocolic intussusception and its variants: a sonographic-pathological correlative study  (Co-Investigator)

1987-1989 [Pharmax Ltd and Roussel Laboratories Ltd] Selective decontamination on colonisation and infection rates in a neonatal surgical unit  (Co-Investigator)

1985-1986 [University Research Grant (Hong Kong)] Evaluation of diagnostic techniques and early and late results of the treatment of biliary atresia to hepaticoportoenterostomy  (Co-Investigator)

1985-1987 [University Research Grant (Hong Kong)] Gastric emptying after posterior trunkal vagotomy with seromyotomy of the anterior lesser curve assessed by epigastric impedance  (Co-Investigator)

- [Health and Medical Research Fund/HMRF] Towards establishing a genetic risk profile for Hirschsprung disease: pathway-centric approach to model polygenic risk  (Co-Investigator)

- [Health and Medical Research Fund/HMRF] Functional interrogation of non-coding regulatory regions identified from Hirschsprung disease patients  (Co-Investigator)

- [Health and Medical Research Fund/HMRF] Organoid systems to study the effect of steroid in modulating immune-mediated inflammation in biliary atresia: a bridge to therapeutic application  (Co-Investigator)

- [RGC Central Allocation for fundable not funded project] A clinico-radiologico-pathological study of the development, progression and treatment of intussusception using an animal model  (Co-Investigator)

- [S.K. Yee Medical Research Fund] Neural crest-derived cells: role in functional repair of the nervous system  (Co-Investigator)

- [S.K. Yee Medical Research Fund] Provision of modern surgical care to poor children with congenital anomalies in southern China  (Co-Investigator)

- [Studies Related to Melamine Incident] The melamine milk – kidney and developmental toxicity: impact on the foetus and the disease development later in life  (Co-Investigator)

2021-2022 [RGC Collaborative Research Fund/CRF] Integrative multi-omics and niche biology approach for precision medicine of Hirschsprung disease  (Co-Principal Investigator)